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Trusted by 1M+ Customers | 30-Day Supply
Daily Metabolic Balance You Can Feel*
LIPOSOMAL BERBERINE
When your metabolism processes carbohydrates efficiently, daily energy stays steady and stubborn cravings quiet down. LipoAvail® liposomal berberine with cinnamon, milk thistle, and chromium supports whole-body metabolic and cardiovascular health, from $0.98 a day.*
- 33× More Bioavailable†
- 1,500 mg Daily Complex
- 4 Researched Ingredients
- Third-Party Tested
- Vegetarian Capsules
- 60-Day Money-Back Guarantee
Best Value: Get 0% Off + Free Gift
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Skip, change or cancel anytime
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60-day money-back guarantee
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60-Day Money Back Guarantee
Third-Party Tested
Free Shipping on US orders
Manufactured in the U.S.A.
Supplement Facts
** Daily Value (DV) not established.
Other Ingredients: vegetable capsule (hydroxypropyl methylcellulose), microcrystalline cellulose, vegetable magnesium stearate, silicon dioxide.
Take back control of how your body handles food.*
Six ways one daily routine supports you, from your first meal to your last.

Steady post-meal glucose*
Supports healthy blood sugar balance after meals, so you avoid sharp spikes and sudden dips.*

Metabolism that keeps up*
Helps your body turn carbs and fats into usable energy.

Easier weight management*
Supports a healthy weight alongside the way you already eat and move.

Healthy cholesterol and heart*
Supports healthy lipid metabolism to help maintain cholesterol and triglyceride levels already in the normal range.*

Active liver metabolism*
Delivers 250 mg of milk thistle to support the liver's role in processing fats and glucose.*

Fewer cravings, steady energy*
Helps calm between-meal sugar cravings and keeps your daily energy steady through the afternoon slump.*
What's inside each serving
Four ingredients, one routine: 3 capsules a day with a meal.
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Provides 500 mg berberine HCl. Berberine is studied in more than 30 human trials for how the body handles sugar and fats. Ours is wrapped in sunflower lecithin to support uptake.
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True Ceylon cinnamon, a 10:1 bark extract standardised to 38 mg polyphenols, to support a calmer rise after meals.
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An essential trace mineral that helps your cells convert dietary fats, proteins, and carbohydrates into clean, usable daily energy.*
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A 50:1 seed extract standardised to 200 mg silymarin, to support everyday liver function.
Supplement Facts
Serving size 3 vegetarian capsules
Servings per container 30
| Amount per serving | % DV | |
|---|---|---|
| Chromium (as chromium picolinate) | 200 mcg | 571% |
| LipoAvail® Liposomal Berberine HCl (berberine HCl, sunflower lecithin) providing berberine HCl 500 mg | 1,000 mg | ** |
| Ceylon cinnamon bark 10:1 extract, polyphenols 38 mg | 250 mg | ** |
| Milk thistle seed 50:1 extract, silymarin 200 mg | 250 mg | ** |
** Daily value not established. Other ingredients: vegetable capsule (hydroxypropyl methylcellulose), microcrystalline cellulose, vegetable magnesium stearate, silicon dioxide.
Why liposomal berberine
Berberine is naturally hard for the body to absorb. LipoAvail® made it 33× more bioavailable.†
Phospholipid layer(sunflower lecithin) Berberine HCl inside
- 1Plain berberine is poorly absorbed
Most of a plain dose never reaches the blood.
- 2A phospholipid layer carries it
LipoAvail® wraps berberine HCl in sunflower lecithin.
- 333× more bioavailable
Compared with regular berberine HCl in a pre-clinical study.†
- 4Same 3 capsules a day
No change to your routine.
What the next 12 weeks can look like

- Weeks 1 to 2Many people notice steadier energy between meals.
- Weeks 3 to 4Cravings for something sweet often feel quieter.
- Month 2Metabolic balance supports easier daily weight management and steady focus.*
- Month 3Supports healthy blood sugar, cholesterol, and waistline markers over time.*
3 capsules a day, with a meal
What the studies measured
Pooled results from published human trials of plain berberine at 0.9 to 1.5 g a day, compared with control.
Liu 2025, Front Pharmacol 16:1572197
Certificate of Analysis & Testing
Exceptional quality isn't aspirational, it's our standard. Transparency is key to building trust, and that's why we provide access to our Certificates of Analysis (COA) & Third-Party Testing Results.
Third-Party Testing
Discover the outcomes of our third-party testing, validating the quality and purity of our product.
The formula breakdown
Not all berberineis built the same.
Compare delivery, supporting botanicals, and certified quality before you choose.
ToniiqLiposomal |
GenericBerberine |
CinnamonBlend Pouch |
|
|---|---|---|---|
| Total Formula | 1,500 mg | 500 mgunverified | 1,500 mg |
| Berberine Form | Liposomal | Plain HCl | Plain HCl |
| Relative Absorption | 33׆pre-clinical | Low | Low |
| Milk Thistle | 250 mg | None | None |
| Chromium | 200 mcg | None | None |
| Lab Tested | YesCOA available | Unknown | Lab tested |
| NSF Facility Certified | Yes | Unknown | Not stated |
| Guarantee | 60 days | Varies | 30 days |
| Cost Per Day | $0.983-month plan | Varies | $1.00sale price |
| HSA/FSA Eligible | Yes | Varies | Not stated |
Customer Reviews
- 4.9
- 817 reviews across Toniiq
- 99%
- would recommend
Liposomal Berberine: 5.0 (1 review) Most reviews below are for our other berberine products, named on each card.
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Works well
Works well with a CGM to see an improvement in glucose levels and lower spiking.
Ann-Marie W.
Review for Liposomal Berberine
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Toniiq Berberine really works..its authentic
I have been using Toniiq brand berberine for two months and I highly recommend it. My midday crashes have ended and I don't experience the evening cravings either. This supplement does as advertised...the food noise is gone. With consistent use, excercise and rest I have lost pounds and inches and didn't sabotage my efforts giving into cravings when blood sugar would crash and in the evening when i found it hard to resist adding those extra calorie snacks.
Tracy S.
Review for Berberine 97%
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A supplement that actually does something
I have been using this product for a few years and I believe it actually works to better control my blood sugar. No panacea but one of the few supplements that I have taken that I feel really does something.I recommend it and I also recommend the company. They (Toniq) produce high quality supplements at very reasonable prices.
Fred F.
Review for Berberine 1500
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Premium quality Berberine
Only purchase your supplements from vendors that have premium ingredients and display their 3rd party test results. I only have 3 such vendors, and Toniiq is one of the best!
Daniel S.
Review for Berberine 97%
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Good, but could be better
I've been taking Toniiq berberine for over a year now, and it has helped blunt my food cravings. I'm impressed with the company and the product. I wish you would make a phytosome version of berberine and combine it with black pepper extract. Just a thought!
Cheryl H.
Review for Berberine 97%
Free US Delivery
Free shipping on all U.S. orders.
Good Manufacturing Practice
Our Toniiq formulas are manufactured in the U.S.A. in a GMP-Certified Facility.
60-Day Money-Back Guarantee
Not right for you? You have a 60-day money-back guarantee.
Ingredient Safety System
All our Toniiq products are third-party lab tested for every batch.
Verified Botanical Potency
A Research & Development team rigorously verifies all ingredients with quality as our ethos.

Reviewed by a longevity physician.
Berberine is one of the most studied plant compounds for healthy blood sugar and metabolism. The challenge has always been absorption: plain berberine is poorly absorbed, so much of each dose never reaches the blood.
What caught my attention here is that the berberine is delivered in a liposome, and it is paired with Ceylon cinnamon, chromium and milk thistle at sensible amounts.
In my experience, people stay with what is simple. Three capsules a day with a meal is a routine that is easy to keep.
Dr. Fernando Soares Moreira, MD
Harvard Medical School · Angiology & Lifestyle Medicine · Healthy Longevity Medicine Society
Dr. Fernando Soares Moreira, MD is a medical advisor to Toniiq.

Liposomal Berberine
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
†Relative bioavailability vs regular berberine HCl in a pre-clinical study by EffePharm, maker of LipoAvail®.
LipoAvail® is a registered trademark of EffePharm Ltd.
Study results describe berberine, not this formula.
Comparison based on publicly available label and pricing, as of 6 Nov 2026.
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